Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive
نویسندگان
چکیده
منابع مشابه
Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive.
Acid-sensing ion channels (ASICs) are trimeric cation-selective ion channels activated by protons in the physiological range. Recent reports have revealed that postsynaptically localized ASICs contribute to the excitatory postsynaptic current by responding to the transient acidification of the synaptic cleft that accompanies neurotransmission. In response to such brief acidic transients, both r...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2017
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1620508114